wkio153

What Are Psychedelic Drugs Hallucinogenics? Although it is certainly true that the salient pharmacology of all psychedelics in animal models seems to be an agonist action at 5-HT2A receptors, the complex neuropharmacology of other types of psychedelics, especially LSD, is not as well studied in animal models. Carter et al. found that psilocybin significantly increased four of the five factors in the 5D-ASC, but only the factor of reduced vigilance remained significantly elevated after ketanserin pretreatment. Performance on the tracking task varied inversely with the number of targets subjects had to track, and it dropped off markedly when the number of targets exceeded three. The number of dots successfully tracked was significantly reduced from placebo in both the psilocybin and psilocybin plus ketanserin pretreatment conditions; ketanserin alone had no effect. In the spatial working memory task, psilocybin had no significant effect on the number of boxes remembered correctly in se